Bufotoxins are a family of toxic steroid lactones . They occur in the parotoid glands , skin and poison of many toads ( genus Bufo ) and other amphibians, and in some plants and mushrooms.    The exact composition varies greatly with the specific source of the toxin. It can contain: 5-MeO-DMT , bufagins , bufalin , bufotalin , bufotenin , bufothionine , epinephrine , norepinephrine , and serotonin . The term bufotoxin can also be used specifically to describe the conjugate of a bufagin with suberylargine. 
I have somewhat extensively studied DNP prior to, during and after my own experiments with this incredibly enticing poison. Surely you didn’t think I was writing all this based on sheer conjecture, hypothesis, and study? There is also some great DNP dialoguing within my Steroid .com signature.
No matter how safe you hear a given herb, chemical, or drug (regardless of dosage) is there is always the possibility of individual sensitivities. This issue becomes greatly magnified with regard to poisons because of the potential for serious injury and fatality. Even the name Di-NITRO-phenol is remarkably engaging to a gear user and “no” proper administration without pre-existing hypersensitivities won’t kill you, but it does all come down to a single truth. A truth you may have arrived at prior to the halfway mark in this piece, the same truth that the author of a great documented journey through the DNP experience, ‘The Inferno: My Week on DNP’ (http://-/portal_includes/articles/2006/06-068-), Vets and Hall-of-Famers like Marcus, Nark, Giant, Booz - just ask them, myself (magic32) and numerous others have come to realize…
The most common adverse reactions about Chinese coptis root are vomiting and nausea in large dose taken in a long term. What’s more, it should be avoided by patients who are using antihypertensive medications and infants with jaundice. TCM wise, it shouldn’t be used in those who are suffering from deficiency-cold in spleen and stomach because overdose or long-term use of extremely cold-bitter natured herb may lead to the impairment of spleen and stomach. In addition, use with care in the case of deficiency of yin and body fluid impairment.