During conventional pharmacologic dose corticosteroid therapy, ACTH production is inhibited with subsequent suppression of cortisol production by the adrenal cortex. Recovery time for normal HPA activity is variable depending upon the dose and duration of treatment. During this time the patient is vulnerable to any stressful situation. Although it has been shown that there is considerably less adrenal suppression following a single morning dose of prednisolone (10 mg) as opposed to a quarter of that dose administered every six hours, there is evidence that some suppressive effect on adrenal activity may be carried over into the following day when pharmacologic doses are used. Further, it has been shown that a single dose of certain corticosteroids will produce adrenal cortical suppression for two or more days. Other corticoids, including methylprednisolone, hydrocortisone, prednisone, and prednisolone, are considered to be short acting (producing adrenal cortical suppression for 1¼ to 1½ days following a single dose) and thus are recommended for alternate day therapy.
If you suffer from plantar fasciitis, you might think perhaps you should rest your feet, but it’s actually better for you to keep on the move. Plantar fasciitis affects the band of tissue connecting your heel bone to your toes, and can cause stabbing pains when walking. A treatment for it is to keep moving, but make sure you don’t overdo it. Keep your mileage and speed down if you begin experiencing pain, and place an ice pack under your foot for 15 minutes after you’ve finished walking. An alternative is to roll a frozen bottle of water under your foot for 10 to 15 minutes instead. Adding support to your foot can also help, so using an insole in your shoe or wrapping your foot with athletic tape is also recommended. To find out more about this, read this guide to Walking With Plantar Fasciitis .